Abstract:

We have previously shown that bis(phosphinic amide)-phosphine oxides can be accessed via directed ortho lithiation (DoM) of phosphinic amides. The tridentate ligand was the basis for the development of membrane and optical fiber luminescence sensors. We envisaged that this methodology could be extended to the synthesis of new hemilabile O,N-chelating ligands. Here we describe the preparation of pirazoloquinazolinephosphinic amide ligands through condensation of o-formylphosphinic amides with 2-pyrazolylanilines followed by oxidation and their complexation behavior towards zinc salts.