Synthesis of meso-tetra-(5-iodo-thien-2-yl)-porphyrin; an intermediate for cross-coupling reactions

Synthesis of meso-tetra-(5-iodo-thien-2-yl)-porphyrin; an intermediate for cross-coupling reactions

Donatoni, Maria C.; Vieira, Ygor W.; Brocksom, Timothy J.; Oliveira, Kleber T. de

Abstract:

The synthesis of new porphyrins has become a major challenge, mainly due to their wide range of applications, including photochemical cells and photodynamic therapy (PDT). With the advent of one-pot processes for the synthesis of meso substituted porphyrins, the number of these compounds has increased considerably. Porphyrins with meso-thienyl groups can also be used as building blocks for new porphyrins. One way to functionalize these compounds is the Heck-Mizoroki and Sonogashira cross coupling reactions. We now propose the synthesis of meso-thien-2-yl-porphyrins functionalized with iodine, ready for cross-coupling reactions.

The synthesis of new porphyrins has become a major challenge, mainly due to their wide range of applications, including photochemical cells and photodynamic therapy (PDT). With the advent of one-pot processes for the synthesis of meso substituted porphyrins, the number of these compounds has increased considerably. Porphyrins with meso-thienyl groups can also be used as building blocks for new porphyrins. One way to functionalize these compounds is the Heck-Mizoroki and Sonogashira cross coupling reactions. We now propose the synthesis of meso-thien-2-yl-porphyrins functionalized with iodine, ready for cross-coupling reactions.

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DOI: 10.5151/chempro-15bmos-BMOS2013_201391315336

Referências bibliográficas

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Como citar:

Donatoni, Maria C.; Vieira, Ygor W.; Brocksom, Timothy J.; Oliveira, Kleber T. de; "Synthesis of meso-tetra-(5-iodo-thien-2-yl)-porphyrin; an intermediate for cross-coupling reactions", p-73-73. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_201391315336