Synthesis and photophysical properties of 2,5-diarylindolizines

Synthesis and photophysical properties of 2,5-diarylindolizines

Souza, Camila R.; Amaral, Mônica F. Z. J.; Clososki, Giuliano C.

Abstract:

The synthesis of fluorescent molecules has received considerable attention since these compounds can be used as electroluminescent materials, dyes and biomarkers. Indolizines are important N-heterocyclic compounds that present interesting pharmacological effects. For example, they can function as anti-inflammatory agents, calcium entry blockers, cardiovascular and anti-tuberculosis agents. Following our interest in the functionalization of aromatic and heterocyclic compounds using organometallic reagents, in this study we have studied the preparation of a library of 2,5-diaryl indolizines and investigated the photophysical properties of this new compounds.

The synthesis of fluorescent molecules has received considerable attention since these compounds can be used as electroluminescent materials, dyes and biomarkers. Indolizines are important N-heterocyclic compounds that present interesting pharmacological effects. For example, they can function as anti-inflammatory agents, calcium entry blockers, cardiovascular and anti-tuberculosis agents. Following our interest in the functionalization of aromatic and heterocyclic compounds using organometallic reagents, in this study we have studied the preparation of a library of 2,5-diaryl indolizines and investigated the photophysical properties of this new compounds.

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013912135111

Referências bibliográficas

• [1] 1 Liu, B.;, Wang, Z.;, Wu., N. et al; Chem. Eur. J. 2012, 18, 1599 -1603.(b)
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• [3] 2 Gundersen, L. L.; Negussie, A. H.; Rise, F.; et al. Arch. Pharm. Pharm.
• [4] Med. Chem. 2003, 336, 191-195

Como citar:

Souza, Camila R.; Amaral, Mônica F. Z. J.; Clososki, Giuliano C.; "Synthesis and photophysical properties of 2,5-diarylindolizines", p-211-211. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_2013912135111