Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

Abstract - Open Access.

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Peptide and cyclopetide synthesis via Ugi and click reactions under microwave irradiation and in continuous flow system

Salvador, Carlos Eduardo M. ; Brito, José Giovanni L. ; Miranda, Leandro Soter de M. ; Souza, Rodrigo O. M. A. ; Andrade, Carlos Kleber Z. ;

Abstract:

Cyclopeptides usually stand out due to their structural characteristics and their physico-chemical and biological properties of interest for use as therapeutic agents. The increasing use of microreactors as a promising technology for the synthesis of compounds with pharmaceutical application and the absence of reports in the literature investigating the Ugi / Click reactions in cyclopeptide synthesis in continuous flow systems were the major motivations for this work.

Abstract:

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Palavras-chave: Click reaction, continuous flow, Ugi reaction,

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013915235633

Referências bibliográficas
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  • [4] 3 - Glasnov, T. N.; Kappe, C. O. Chem. Eur. J. 2011, 17, 11956.
Como citar:

Salvador, Carlos Eduardo M.; Brito, José Giovanni L.; Miranda, Leandro Soter de M.; Souza, Rodrigo O. M. A.; Andrade, Carlos Kleber Z.; "Peptide and cyclopetide synthesis via Ugi and click reactions under microwave irradiation and in continuous flow system", p. 281 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_2013915235633

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