Oxireduction’s Studies of Arytetralone and Aryltetralol Mediated by Rhodotorula sp

Oxireduction’s Studies of Arytetralone and Aryltetralol Mediated by Rhodotorula sp

Capeletto, Marina G.; Jr, Luiz S. Longo; Batista, Wagner L.; Bianco, Graziela G.

Abstract:

The Aristolochiaceae family presented extracts with antimalarial activity. Some aryltetralones lignans were isolated from Holostylis reniformis (Figure 1) and those are responsible for this antimalarical activity. Biocatalysis has been shown to be a strong strategy to obtain enantiomerically pure substances, because it promotes reactions with high chemo-, regio- and stereoseletivity. This methodology show to be important because it’s environmentally favorable, since various principles of Green Chemistry may be contemplated like possibility of using water as a solvent, especially when we using whole cells. These whole cells contain all necessary cofactors to promote the desired reaction and they are able to recycle them.

The Aristolochiaceae family presented extracts with antimalarial activity. Some aryltetralones lignans were isolated from Holostylis reniformis (Figure 1) and those are responsible for this antimalarical activity. Biocatalysis has been shown to be a strong strategy to obtain enantiomerically pure substances, because it promotes reactions with high chemo-, regio- and stereoseletivity. This methodology show to be important because it’s environmentally favorable, since various principles of Green Chemistry may be contemplated like possibility of using water as a solvent, especially when we using whole cells. These whole cells contain all necessary cofactors to promote the desired reaction and they are able to recycle them.

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013818103532

Referências bibliográficas

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Como citar:

Capeletto, Marina G.; Jr, Luiz S. Longo; Batista, Wagner L.; Bianco, Graziela G.; "Oxireduction’s Studies of Arytetralone and Aryltetralol Mediated by Rhodotorula sp", p-161-161. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_2013818103532