NANOASSEMBLIES: COVALENT DERIVATIVES OF NEVIRAPINE WITH POLYETHYNE GLYCOL DIACRYLATE

NANOASSEMBLIES: COVALENT DERIVATIVES OF NEVIRAPINE WITH POLYETHYNE GLYCOL DIACRYLATE

E, Costas do Santos; R., Glisoni; L., Fabian; A., Sosnik; A., Moglioni

Abstract:

The design of nano-molecular transporters such as “hydrogels”, based on PEG and chemically modified active compounds, significantly improves their hidrosolubilization.1 Considering that nevirapine (NVP) has proven highly effective in the highly active antiretroviral therapy (HAART), when used as first choice for the treatment of antiretroviral-naïve patients, but has low aqueous solubility, investigation about its improvement is necessary.

The design of nano-molecular transporters such as “hydrogels”, based on PEG and chemically modified active compounds, significantly improves their hidrosolubilization.1 Considering that nevirapine (NVP) has proven highly effective in the highly active antiretroviral therapy (HAART), when used as first choice for the treatment of antiretroviral-naïve patients, but has low aqueous solubility, investigation about its improvement is necessary.

Palavras-chave:

DOI: 10.5151/chempro-15bmos-BMOS2013_2013913132632

Referências bibliográficas

• [1] 1. Cellesi F., Tirelli n. Journal of Material Science: Material in Medicine, 2005, 16, 559-565.

Como citar:

E, Costas do Santos; R., Glisoni; L., Fabian; A., Sosnik; A., Moglioni; "NANOASSEMBLIES: COVALENT DERIVATIVES OF NEVIRAPINE WITH POLYETHYNE GLYCOL DIACRYLATE", p-226-226. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_2013913132632