Gold-Catalyzed Cyclization of Ynamides and Propargylic Carboxylates

Gold-Catalyzed Cyclization of Ynamides and Propargylic Carboxylates

Wieteck, Marcel; Rettenmeier, Eva; Hashmi, A. Stephen K.

Abstract:

Over the past few years new synthetic methodologies for the preparation of ynamides have led to a huge increase in their use as highly variable building blocks in organic synthesis. Owing to the presence of an electron-withdrawing group ynamides show a perfect balance between stability and reactivity. Furthermore, due to their strongly polarized triple bond, ynamides show a large variety of reactions possibilities. Among these there are, for example addition at the α- or β-position, cycloaddition, ring-closing metathesis, cyclosisomerization

Over the past few years new synthetic methodologies for the preparation of ynamides have led to a huge increase in their use as highly variable building blocks in organic synthesis. Owing to the presence of an electron-withdrawing group ynamides show a perfect balance between stability and reactivity. Furthermore, due to their strongly polarized triple bond, ynamides show a large variety of reactions possibilities. Among these there are, for example addition at the α- or β-position, cycloaddition, ring-closing metathesis, cyclosisomerization

Palavras-chave:

DOI: 10.5151/chempro-15bmos-BMOS2013_2013913161344

Referências bibliográficas

• [1] E. Rettenmeier, A. M. Schuster, M. Rudolph, F. Rominger, C. Gade, A. S. K. Hashmi, Angew. Chem. 2013, 125, 5993-5997; Angew. Chem. Int. Ed. 2013, 52, 5880-5884.

Como citar:

Wieteck, Marcel; Rettenmeier, Eva; Hashmi, A. Stephen K.; "Gold-Catalyzed Cyclization of Ynamides and Propargylic Carboxylates", p-236-236. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_2013913161344