Enzymatic Kinetic Resolution of Hydroxy Furan and Tiophene 2-substituted

Enzymatic Kinetic Resolution of Hydroxy Furan and Tiophene 2-substituted

Pires, D. S. F.; Ferreira, J. G.; Filho, E. F. S.; Princival, J. L.

Abstract:

Chiral non racemic secondary alcohols containing 2- Furan and Tiophene rings are widely widespread compounds in the environment and they also play important role in biochemical process. In addition these compounds can be employed as building blocks in the synthesis of bioactive molecules. However, environmentally harmful reagents and many reaction steps are generally assigned to synthetic methodologies that employ it. Here, we propose a chemoenzymatic methodology to prepare enantioenriched secondary alcohols containing furan and tiophene heterocyclic group.

Chiral non racemic secondary alcohols containing 2- Furan and Tiophene rings are widely widespread compounds in the environment and they also play important role in biochemical process. In addition these compounds can be employed as building blocks in the synthesis of bioactive molecules. However, environmentally harmful reagents and many reaction steps are generally assigned to synthetic methodologies that employ it. Here, we propose a chemoenzymatic methodology to prepare enantioenriched secondary alcohols containing furan and tiophene heterocyclic group.

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DOI: 10.5151/chempro-15bmos-BMOS2013_201391414637

Referências bibliográficas

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Como citar:

Pires, D. S. F.; Ferreira, J. G.; Filho, E. F. S.; Princival, J. L.; "Enzymatic Kinetic Resolution of Hydroxy Furan and Tiophene 2-substituted", p-77-77. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_201391414637