α-Hydroxylation of malonates under mild reaction conditions

α-Hydroxylation of malonates under mild reaction conditions

Peterle, Marcos M.; Marques, Marcelo V.; Sá, Marcus M.

Abstract:

Peroxysulfuric acid and its potassium salt have been known as oxidizing agents for some time. The potassium peroxymonosulfate salt, sold under the commercial name Oxone® (2KHSO5•KHSO4•K2SO4), is a very stable substance and can be easily handled. Oxone has been used in the oxidation of alcohols and C-H bonds, and also in the epoxidation of olefins. In this work, we present a simple method to prepare α- hydroxy malonates of synthetic interest.

Peroxysulfuric acid and its potassium salt have been known as oxidizing agents for some time. The potassium peroxymonosulfate salt, sold under the commercial name Oxone® (2KHSO5•KHSO4•K2SO4), is a very stable substance and can be easily handled. Oxone has been used in the oxidation of alcohols and C-H bonds, and also in the epoxidation of olefins. In this work, we present a simple method to prepare α- hydroxy malonates of synthetic interest.

Palavras-chave:

DOI: 10.5151/chempro-15bmos-BMOS2013_2013820152632

Referências bibliográficas

• [1] 1 Hussain, H.; Green, I. R.; Ahmed, I. Chem. Rev. 2013, 113, 3329.
• [2] 2 Marques, M. V.; Oliveira, C. C.; Correia, C. R. D.; Sá, M. M. Abstract from
• [3] 4th IICGC, 2012, Foz do Iguaçu, Brazil.
• [4] 3 Kumar, D. N.; Reddy, C. R.; Das, B. Synthesis 2011, 3190.

Como citar:

Peterle, Marcos M.; Marques, Marcelo V.; Sá, Marcus M.; "α-Hydroxylation of malonates under mild reaction conditions", p-185-185. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-15bmos-BMOS2013_2013820152632