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EFFECT OF OUTFLOW CANNULA PLACEMENT AND PULSATILITY OF BLOOD PUMPS ON CEREBRAL BLOOD FLOW AND WALL SHEAR STRESS DURING CARDIAC ASSIST

Kaufmann, T. A. S.; Schmitz-Rode, T.; Moritz, A.; Steinseifer, U.;

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Device cannulation to the cardiovascular system (CVS) is an important considera-tion for cardiac assist. Some devices return blood via the ascending aorta, while others place the outflow cannula in the descending aorta. A Computational Fluid Dynamics study in de-pendency on different flow profiles representing different devices was undertaken for both approaches. The main goal was to develop a computational model to analyze the impact of different parameters of Ventricular Assist Devices (VAD) support on flow conditions in gen-eral and cerebral perfusion in particular. A 3D model of the human CVS was reconstructed from Magnetic Resonance Imaging data. A VAD outflow cannula was placed in four different positions inside ascending and proximal descending aorta. Transient numerical simulations were performed for each position assum-ing continuous and physiologically modulated device flow. The physiological flow from the heart was set to zero for a non-beating heart condition and 3 L/min for a weak heart condi-tion. Main flow variables are only slightly affected by the cannulation method but highly affected by the flow profile. Wall shear stress is increased for pulsatile support, whereby arterioscle-rotic plaque embolism might be induced. The cerebral blood flow is increased for cannulation of the descending aorta for each condition.

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Palavras-chave: Computational Fluid Dynamics, Ventricular Assist Devices, Outflow Cannula, Pulsatility, Cerebral Blood Flow.,

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DOI: 10.5151/meceng-wccm2012-18131

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Como citar:

Kaufmann, T. A. S.; Schmitz-Rode, T.; Moritz, A.; Steinseifer, U.; "EFFECT OF OUTFLOW CANNULA PLACEMENT AND PULSATILITY OF BLOOD PUMPS ON CEREBRAL BLOOD FLOW AND WALL SHEAR STRESS DURING CARDIAC ASSIST", p. 822-835 . In: In Proceedings of the 10th World Congress on Computational Mechanics [= Blucher Mechanical Engineering Proceedings, v. 1, n. 1]. São Paulo: Blucher, 2014.
ISSN 2358-0828, DOI 10.5151/meceng-wccm2012-18131

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