Toward the Total Synthesis of (+)-trans-Trikentrin A

Toward the Total Synthesis of (+)-trans-Trikentrin A

Tébéka, Iris R. M.; Jr., Luiz F. Silva

Abstract:

The alkaloid (+)-trans-trikentrin A is a marine natural product isolated in 1986 whose racemic synthesis has already been achieved by our group through a ring contraction key step. Herein we describe our recent afforts toward the total synthesis of (+)-trans-trikentrin A (Scheme 1).

The alkaloid (+)-trans-trikentrin A is a marine natural product isolated in 1986 whose racemic synthesis has already been achieved by our group through a ring contraction key step. Herein we describe our recent afforts toward the total synthesis of (+)-trans-trikentrin A (Scheme 1).

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DOI: 10.5151/chempro-14bmos-R0209-1

Referências bibliográficas

• [1] 1 Capon, R. J.; MacLeod, J. K.; Scammels, P. J. Tetrahedron 1986, 42, 6545.
• [2] 2 Silva, L. F., Jr.; Craveiro, M. V. Org. Lett. 2008, 10, 5417.
• [3] 3 Dambacher, J.; Anness, R.; Pollock, P.; Bergdahl, M. Tetrahedron 2004, 60, 2097.
• [4] 4 Chow, R.; Kocienski, P. J.; Kuhl, A.; LeBrazidec, J.-Y.; Muir, K.; Fish, P. J. Chem. Soc., Perkin Trans. 1 2001, 2344.
• [5] 5 Paál, T. A.; Forró, E.; Fülöp, F.; Liljebad, A.; Kanerva, L. T. Tetrahedron: Asymmetry 2008, 19, 2784.

Como citar:

Tébéka, Iris R. M.; Jr., Luiz F. Silva; "Toward the Total Synthesis of (+)-trans-Trikentrin A", p-209-209. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0209-1