Synthesis of tetrahydropiridines by one-pot multicomponent reaction using Niobium Pentachloride.

Synthesis of tetrahydropiridines by one-pot multicomponent reaction using Niobium Pentachloride.

Martins, Lucas Michelão; Silva, Bruno Henrique Sacoman Torquato da; Silva-Filho, e Luiz Carlos da

Abstract:

Tetrahydropiridines occurs in nature in great quantities, and are known to be important in the pharmaceutical industry. Some of them also act as therapeutic agents, exhibit antihypertensive, antibacterial, anticonvulsant and anti-inflammatory activities. Knowing that Tetrahydropiridines derivatives can be synthesized from the Multicomponent reaction (MCRs) in the presence of different catalysts (InCl3, TBATB, CAN, BDMS and others), we present the synthesis using NbCl5.

Tetrahydropiridines occurs in nature in great quantities, and are known to be important in the pharmaceutical industry. Some of them also act as therapeutic agents, exhibit antihypertensive, antibacterial, anticonvulsant and anti-inflammatory activities. Knowing that Tetrahydropiridines derivatives can be synthesized from the Multicomponent reaction (MCRs) in the presence of different catalysts (InCl3, TBATB, CAN, BDMS and others), we present the synthesis using NbCl5.

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DOI: 10.5151/chempro-14bmos-R0110-1

Referências bibliográficas

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Como citar:

Martins, Lucas Michelão; Silva, Bruno Henrique Sacoman Torquato da; Silva-Filho, e Luiz Carlos da; "Synthesis of tetrahydropiridines by one-pot multicomponent reaction using Niobium Pentachloride.", p-110-110. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0110-1