Synthesis of octa-b-formylporphyrins as templates for functionalized tetrabenzoporphyrins

Synthesis of octa-b-formylporphyrins as templates for functionalized tetrabenzoporphyrins

Assis, Francisco F. de; Souza, Juliana M. de; Assis, Beatriz H. K.; Brocksom, Timothy J.; Oliveira, Kleber T. de

Abstract:

Porphyrins with benzene rings fused at the β positions are named benzoporphyrins (Figure 1). These structures have been investigated in a wide range of applications like: light-emitting diodes, photodynamic therapy, biomedical sensing and imaging. Synthetic modifications of _-functionalized porphyrins have been proposed as an interesting way to synthesize such molecules. Working with this idea, we are investigating the synthesis of an octa-b-formylporphyrin, which will be used for the preparation of new functionalized tetrabenzoporphyrins, to be studied as photosensitizers in photodynamic therapy (PDT).

Porphyrins with benzene rings fused at the β positions are named benzoporphyrins (Figure 1). These structures have been investigated in a wide range of applications like: light-emitting diodes, photodynamic therapy, biomedical sensing and imaging. Synthetic modifications of _-functionalized porphyrins have been proposed as an interesting way to synthesize such molecules. Working with this idea, we are investigating the synthesis of an octa-b-formylporphyrin, which will be used for the preparation of new functionalized tetrabenzoporphyrins, to be studied as photosensitizers in photodynamic therapy (PDT).

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DOI: 10.5151/chempro-14bmos-R0195-1

Referências bibliográficas

• [1] 1 Silva, A. M. G.; de Oliveira, K. T.; Faustino, M. A. F.; Neves, M.; Tome, A. C.; Silva, A. M. S.; Cavaleiro, J. A. S.; Brandao, P.; Felix, V. Eur. J. Org. Chem. 2008, 704.
• [2] 2 Deshpande, R.; Jiang, L.; Shimidt, G.; Rakovan, J.; Wang, X.; Wheeler, K. e Wang, H. Org.Lett 2009, 11, 4251.
• [3] 3 Firouzabadi, H.; Vessal, B. e Naderi, M. Tetrahedrom Lett. 1982, 23, 1847.

Como citar:

Assis, Francisco F. de; Souza, Juliana M. de; Assis, Beatriz H. K.; Brocksom, Timothy J.; Oliveira, Kleber T. de; "Synthesis of octa-b-formylporphyrins as templates for functionalized tetrabenzoporphyrins", p-195-195. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0195-1