Abstract:

Porphyrins with benzene rings fused at the β positions are named benzoporphyrins (Figure 1). These structures have been investigated in a wide range of applications like: light-emitting diodes, photodynamic therapy, biomedical sensing and imaging. Synthetic modifications of _-functionalized porphyrins have been proposed as an interesting way to synthesize such molecules. Working with this idea, we are investigating the synthesis of an octa-b-formylporphyrin, which will be used for the preparation of new functionalized tetrabenzoporphyrins, to be studied as photosensitizers in photodynamic therapy (PDT).