SCNS. 14. Evidence of antidepressant effect of Riparin I, isolated from Aniba riparia, in a model depression chronic in mice

SCNS. 14. Evidence of antidepressant effect of Riparin I, isolated from Aniba riparia, in a model depression chronic in mice

OLIVEIRA, I.C.M.; VASCONCELOS, A.S.; VIDAL, L.M.T.; RODRIGUES, F.A.P.; SOUSA, F.C.F.

Abstract:

Major Depressant Disorder is one of the most common neuropsychiatric disorders and affects 17-20% of the world population. Despite scientific efforts, its treatment still presents itself with a limited efficacy and a delayed start-up effect. In this context, natural products are a potential source of new drugs. Riparin I (Rip I), one alcamide isolated from Aniba Riparia, has presented promising results. In pre-clinic trials, it has unchained predictive effects of antidepressant and anxiolytic activities in acute behavioral models of depression and anxiety.

Major Depressant Disorder is one of the most common neuropsychiatric disorders and affects 17-20% of the world population. Despite scientific efforts, its treatment still presents itself with a limited efficacy and a delayed start-up effect. In this context, natural products are a potential source of new drugs. Riparin I (Rip I), one alcamide isolated from Aniba Riparia, has presented promising results. In pre-clinic trials, it has unchained predictive effects of antidepressant and anxiolytic activities in acute behavioral models of depression and anxiety.

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DOI: 10.5151/isnm-sine19

Como citar:

OLIVEIRA, I.C.M.; VASCONCELOS, A.S.; VIDAL, L.M.T.; RODRIGUES, F.A.P.; SOUSA, F.C.F.; "SCNS. 14. Evidence of antidepressant effect of Riparin I, isolated from Aniba riparia, in a model depression chronic in mice", p-24-24. In: In I International Symposium in Neuroscience Meeting, 2013 [Blucher Neuroscience Proceedings n.1 v.1]. São Paulo: Blucher, 2014.
ISSN 2357772x, DOI 10.5151/isnm-sine19