SCMS.04. Effect of sodium nitrite in a model of depressive-like behavior induced by LPS in mice

SCMS.04. Effect of sodium nitrite in a model of depressive-like behavior induced by LPS in mice

TOMAZ, V.S.; CORDEIRO, R.C.; MONTEIRO, I.O.; ROCHA, N.F.M.; MACÊDO, D.S.

Abstract:

Psychiatric disorders, including depression, are among the leading causes of disability worldwide. In this context, research about new pathways involved in the pathophysiology of this mental disorder with the search of new targets for the treatment of this disorder has been widely studied. Studies confirm that the increased levels of nitrite are directly related to depression, based on this hypothesis we consider that the administration of organic nitrites can accentuate the depressive-like behavior in an experimental model.

Psychiatric disorders, including depression, are among the leading causes of disability worldwide. In this context, research about new pathways involved in the pathophysiology of this mental disorder with the search of new targets for the treatment of this disorder has been widely studied. Studies confirm that the increased levels of nitrite are directly related to depression, based on this hypothesis we consider that the administration of organic nitrites can accentuate the depressive-like behavior in an experimental model.

Palavras-chave:

DOI: 10.5151/isnm-sine9

Como citar:

TOMAZ, V.S.; CORDEIRO, R.C.; MONTEIRO, I.O.; ROCHA, N.F.M.; MACÊDO, D.S.; "SCMS.04. Effect of sodium nitrite in a model of depressive-like behavior induced by LPS in mice", p-14-14. In: In I International Symposium in Neuroscience Meeting, 2013 [Blucher Neuroscience Proceedings n.1 v.1]. São Paulo: Blucher, 2014.
ISSN 2357772x, DOI 10.5151/isnm-sine9