Lithium Organochalcogenides Promoting Michael-aldol Tandem Reactions

Lithium Organochalcogenides Promoting Michael-aldol Tandem Reactions

Sousa, Bruno A. de; Zanin, Fábio G.; Santos, Alcindo A. Dos

Abstract:

Tandem reactions show itself as a very attractive methodology in the scope of total synthesis, allowing important transformations in the construction of multifunctionalized carbon skeletons. Furthermore, was proven that lithium organochalcogenides are good nucleophiles in Michael-aldol-tandem reactions and the resulting adducts are considered immediate precursors of Baylis-Hillman adducts.

Tandem reactions show itself as a very attractive methodology in the scope of total synthesis, allowing important transformations in the construction of multifunctionalized carbon skeletons. Furthermore, was proven that lithium organochalcogenides are good nucleophiles in Michael-aldol-tandem reactions and the resulting adducts are considered immediate precursors of Baylis-Hillman adducts.

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DOI: 10.5151/chempro-14bmos-R0297-1

Referências bibliográficas

• [1] 1 Parsons, P. J.; Penkett, C. S.; Shell, A. J. Chem. Rev. 1996, 96, 195-206.
• [2] 2 Keppler, A. F.; Gariani, R. A.; Lopes, D. G.; Comasseto, J. V. Tetrahedron Lett. 2009, 50, 2181.

Como citar:

Sousa, Bruno A. de; Zanin, Fábio G.; Santos, Alcindo A. Dos; "Lithium Organochalcogenides Promoting Michael-aldol Tandem Reactions", p-297-297. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0297-1