Electrophilic Cyclization of (Z)-Thiobutenynes: Synthesis of 3-Iodothiophenes

Electrophilic Cyclization of (Z)-Thiobutenynes: Synthesis of 3-Iodothiophenes

Santana, Amanda S.; Cassemiro, Nadla S.; Carvalho, Diego B. de; Jr, Palimécio G. Guerrero; Barbosa, Sandro L.; Viana, Luiz H.; Hurtado, Gabriela R.; Baroni, Adriano C. M.

Abstract:

Heteroaromatic organic compounds containing the thiophenic structural unit has been isolated from natural sources like animals and plants. They are also found in synthetic compounds such as agrochemicals, pharmaceuticals, photographic and electronics products. This heterocycle is also widely used in Medicinal Chemistry in design of new drugs, due it is considered a classic bioisoster of the benzenic and furanic rings.

Heteroaromatic organic compounds containing the thiophenic structural unit has been isolated from natural sources like animals and plants. They are also found in synthetic compounds such as agrochemicals, pharmaceuticals, photographic and electronics products. This heterocycle is also widely used in Medicinal Chemistry in design of new drugs, due it is considered a classic bioisoster of the benzenic and furanic rings.

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DOI: 10.5151/chempro-14bmos-R0369-1

Referências bibliográficas

• [1] 1 Kaniskan, N.; Elmali, D.; Civcir, P. U. Arkivoc 2008, 17, e referências citadas.
• [2] 2 Wermuth, C. G. The Practice of Medicinal Chemistry, 2nd ed., Elsevier - Academic Pres, 2004.

Como citar:

Santana, Amanda S.; Cassemiro, Nadla S.; Carvalho, Diego B. de; Jr, Palimécio G. Guerrero; Barbosa, Sandro L.; Viana, Luiz H.; Hurtado, Gabriela R.; Baroni, Adriano C. M.; "Electrophilic Cyclization of (Z)-Thiobutenynes: Synthesis of 3-Iodothiophenes", p-369-369. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0369-1