Construction of Polyarylated Fluorenones via chemoselective Ru- and Pd-Catalyzed Suzuki Cross-Coupling Reactions

Construction of Polyarylated Fluorenones via chemoselective Ru- and Pd-Catalyzed Suzuki Cross-Coupling Reactions

da Silva, A. J. M.; Schneider, C.; Snieckus, V.

Abstract:

The importance of fluoren-9-one (1), found in many biologically active products, has been emphasized in organic chemistry. It consists of essential structural backbone of various pharmaceuticals. Also number of natural products have been found containing fluoren-9-ones showing a range of biological acitivities; e.g. dengibsin, dengobsinin, dendroflorin and kinobscurinone. Utility of fluorenone derivatives as photosensitizers in organic photoconductor devices and their electrical and optical properties are also important.

The importance of fluoren-9-one (1), found in many biologically active products, has been emphasized in organic chemistry. It consists of essential structural backbone of various pharmaceuticals. Also number of natural products have been found containing fluoren-9-ones showing a range of biological acitivities; e.g. dengibsin, dengobsinin, dendroflorin and kinobscurinone. Utility of fluorenone derivatives as photosensitizers in organic photoconductor devices and their electrical and optical properties are also important.

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DOI: 10.5151/chempro-14bmos-R0007-1

Referências bibliográficas

• [1] 1-Perry, P. J.; Read, M. A.; Davies, R. T.; Gowan, S. M.;Reszka, A. P.; Wood, A. A.; Kelland, L. R.; Neidle, S. J. Med. Chem. 1999, 42, 2679.
• [2] 2-Hartung, C. G.; Snieckus, V. Modern Arene Chemistry; Astruc, D., Ed.; Wiley-VCH: New York, 2002;330. 3-Tilly, D.; Samanta, S. S.; Faigl, F.; Mortier, J. Tetrahedron Lett. 2002, 43, 8347. 4-Kakiuchi,F; Usui, M.; Ueno, S.; Naoto Chatani, N.; Murai, S., J. Am. Chem. Soc. 2002, 126, 2706.

Como citar:

da Silva, A. J. M.; Schneider, C.; Snieckus, V.; "Construction of Polyarylated Fluorenones via chemoselective Ru- and Pd-Catalyzed Suzuki Cross-Coupling Reactions", p-7-7. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0007-1