Setembro 2013 vol. 1 num. 1 - Brazilian Meeting on Organic Synthesis 2011

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A new approach to the synthesis of natural product Aripuanin

Lazaro, Aline Simões ; Donate, Paulo Marcos ; Sairre., Mirela Inês de ;

Abstract:

The sesquiterpene (3S,5R,6R,7E,9x)-megastigman- 7-ene-3,5,6,9-tetrol, also known as Aripuanin (1), was isolated from the leaves of Ficus aripuanensis, which belongs to one of the main species of the Amazonian forest used in folk medicine for their several biological properties. In this work, we describe a new synthetic route for the preparation of natural product Aripuanin (1), as outlined in Scheme 1, starting from the readily available commercial β-ionone (2).

Abstract:

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Palavras-chave: Ficus, Aripuanin, Synthesis,

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DOI: 10.5151/chempro-14bmos-R0301-2

Referências bibliográficas
  • [1] 1 M. Nascimento et al.; Fitoterapia 1999, 70, 628.
  • [2] 2 S. Serra et al.; Tetrahedron Asymm. 2007, 18, 2573.
Como citar:

Lazaro, Aline Simões; Donate, Paulo Marcos; Sairre., Mirela Inês de; "A new approach to the synthesis of natural product Aripuanin", p. 301 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-14bmos-R0301-2

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