A Model to Study Intramolecular p−p Stacking Interactions

A Model to Study Intramolecular p−p Stacking Interactions

Cardoso, Flávio Sêga Pereira; Aponick, Aaron

Abstract:

Nature has evolved enzymes as effective catalysts in biological systems. The activity of these macromolecules is governed by a variety of noncovalent interactions. In particular, interactions involving aromatic units play an important role in the behavior of not only biological but also chemical systems. In order to better understand this phenomena, designing chemical models to study these interactions is meaningful. Scheme 1 illustrates a general system containing 2 aromatic units connected by a “linker”. Depending on the nature of the aromatic moieties and the “linker”, the rings could be π-π stacked or not.

Nature has evolved enzymes as effective catalysts in biological systems. The activity of these macromolecules is governed by a variety of noncovalent interactions. In particular, interactions involving aromatic units play an important role in the behavior of not only biological but also chemical systems. In order to better understand this phenomena, designing chemical models to study these interactions is meaningful. Scheme 1 illustrates a general system containing 2 aromatic units connected by a “linker”. Depending on the nature of the aromatic moieties and the “linker”, the rings could be π-π stacked or not.

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DOI: 10.5151/chempro-14bmos-R0045-1

Referências bibliográficas

• [1] 1 Knowles, R. R.; Jacobsen, E. N. Proc. Natl. Acad. Sci. 2010, 107, 20678.
• [2] 2 Meyer, E. A.; Castellano, R. K.; Diederich, F. Angew. Chem., Int. Ed. 2003, 42, 1210–1250.
• [3] 3 I. O. Sutherland, Annu. Rep. NMR Spectrosc., 1971, 4, 71–235.

Como citar:

Cardoso, Flávio Sêga Pereira; Aponick, Aaron; "A Model to Study Intramolecular p−p Stacking Interactions", p-45-45. In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 1, Setembro.2013. São Paulo: Blucher, 2013.
ISSN 23184043, DOI 10.5151/chempro-14bmos-R0045-1