Abstract:

Thioesters and amides have been employed in a wide range of organic transformations. For example, they have been widely used as building blocks for heterocyclic thiazolidinones and thiazinanonas. Thiazolidinones and their derivatives are an important group of compounds that have valuable biological activities. In our research program there is also an interest in improving the methodologies for the preparation of sulfur derivatives using alternative methods like as ultrassom irradiation. So, the aim of this work was the synthesis of amides and thioesteres, intermediate compounds to synthesis of thiazolidinones, using both conventional and sonochemical methodologies