Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

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Regioselective reduction of 1-amino-2,4-dinitrobenzenes

Custódio, Cíntia de Andrade ; Garden, Simon J. ;

Abstract:

The selective reduction of dinitro compounds is an important synthetic strategy for the synthesis of intermediates for dyes, pharmaceuticals and agrochemicals. Reduction of nitro compounds can be performed by a large number of synthetic methodologies including hydrazine with catalytic ferric chloride, NaBH4/Raney nickel, catalytic hydrogenation, or by dissolving metals (Fe, Sn, Zn). However, many of these methods are not chemoselective nor regioselective for the reduction of substituted dinitro aromatics. The present study reports our findings with respect to the regioselective reduction of 1-amino- 2,4-dinitrobenzene derivatives with SnCl2 in EtOAc.

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Palavras-chave: selective reduction, dinitrobenzene, stannous chloride,

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DOI: 10.5151/chempro-15bmos-BMOS2013_2013819201721

Referências bibliográficas
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Como citar:

Custódio, Cíntia de Andrade; Garden, Simon J.; "Regioselective reduction of 1-amino-2,4-dinitrobenzenes", p. 181 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_2013819201721

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