Dezembro 2013 vol. 1 num. 2 - Brazilian Meeting on Organic Synthesis 2013

Abstract - Open Access.

Idioma principal

Preparation of New Prenylated (E)-Chalcones

Santos, *Mariana Bastos dos ; Gullo, Fernanda Patricia ; Dutra, Luiz Antonio ; Mendes-Giannini, Maria José Soares ; Fusco-Almeida, Ana Marisa ; Regasini, Luis Octávio ;

Abstract:

Chalcones comprise one of the main classes of natural products, and their structure is an interesting scaffold for different chemical modifications, including the functional group interconversions. Among the different groups that are correlated to bioactivity of chalcones, the side prenyl chains seem to be related to plasmatic membrane anchorage. For this reason, we have synthesized a series of 20 new O-prenylated chalcones, including isoprenylated, geranylated and farnesylated derivatives. In addition, these compounds were evaluated as antifungal agents.

Abstract:

Palavras-chave: prenylated chalcones, prenylation, Claisen rearrangements,

Palavras-chave:

DOI: 10.5151/chempro-15bmos-BMOS2013_201382002510

Referências bibliográficas
  • [1] 1 Chetana, B. P.; Mahajan, S. K.; and Survana, A. K., J. Sci. Res. 2009, 1, 1
  • [2] 2 Dong, X.; Chen, J.; Jiang, C.; Liu, T. and Hu, Y. Arch. Pharm. Chem. Life Sci. 2009, 342, 428.
Como citar:

Santos, *Mariana Bastos dos; Gullo, Fernanda Patricia; Dutra, Luiz Antonio; Mendes-Giannini, Maria José Soares; Fusco-Almeida, Ana Marisa; Regasini, Luis Octávio; "Preparation of New Prenylated (E)-Chalcones", p. 51 . In: In Blucher Chemistry Proceedings, São Paulo, v. 1, n. 2, Dezembro.2013. São Paulo: Blucher, 2013.
ISSN 2318-4043, DOI 10.5151/chempro-15bmos-BMOS2013_201382002510

últimos 30 dias | último ano | desde a publicação


downloads


visualizações


indexações